Projeto paisagístico para revitalização do Parque Poeta Manuel Bandeira e seu entorno - Cocotá, Rio de Janeiro

O Projeto Paisagístico para o Parque Poeta Manuel Bandeira, localizado no Rio de Janeiro, trata-se de um trabalho de revitalização, proposto para o Trabalho de Conclusão de Curso do curso de Paisagismo, pertencente à Escola de Belas Artes, da Universidade Federal do Rio de Janeiro, UFRJ. A proposta foi fundamentada em pesquisa da área de estudo e análise do local através de auxílio de mapas e visitas a campo para melhor compreender o funcionamento e as demandas da região. Pelas análises, observa-se os usos dos espaços, a circulação de pessoas, as áreas de permanência e verificando a arborização existente. A revitalização sugerida está voltada para o lazer e bem-estar de todos, oferecendo acessibilidade e maior conforto aos usuários

Levantamento da produção de morangos no Oeste catarinense

The objective of the work was to carry out a survey of data on the production of strawberries in the western region of Santa Catarina, which enables the planning of technical assistance actions in the cultivation and development of the production chain. The survey was carried out in 2019, through the application of a questionnaire to Epagri extension workers. The researched data were the number of growers per municipality, cultivation system, number of plants per grower and the cultivars planted. The results show that there are 74 strawberry growers distributed in 81% of the municipalities in the region. The main production system adopted is the semi-hydroponic in elevated benches, which is present in 66% of the properties. Of the 74 growers, 84% are conventional. Regarding the number of cultivated plants, 50% have less than 2500 plants and 74% less than 5000 plants. The predominant cultivars are San Andreas and Albion.O objetivo do trabalho foi realizar um levantamento de dados sobre a produção de morangos na região Oeste Catarinense, que possibilite o planejamento de ações de assistência técnica no cultivo e de desenvolvimento da cadeia produtiva. O levantamento foi realizado no ano de 2019, através da aplicação de um questionário aos extensionistas da Epagri. Os dados pesquisados foram o número de produtores por munícipio, sistema de cultivo, número de plantas por produtor e as cultivares plantadas. Os resultados demonstram que existem 74 produtores de morango distribuídos em 81% dos municípios da região. O principal sistema de produção adotado é o semi-hidropônico em bancadas elevadas que se encontra presente em 66% das propriedades. Dos 74 produtores, 84% produzem no sistema convencional. Em relação ao número de plantas cultivadas, 50% possuem menos de 2500 plantas e 74% menos de 5000 plantas. Os cultivares predominantes são San Andreas e Albion.

Influence of bioactive particles and onium salt on the physicochemical properties of experimental infiltrants

Abstract This study evaluated physicochemical properties of experimental infiltrants after addition of hydroxyapatite nanoparticles (HAp) or 58S bioactive glass (BAG) and diphenyliodonium hexafluorophosphate (DPI). The resin matrix was composed of TEGDMA/Bis-EMA (3:1), 0.5 mol% CQ, and 1 mol% EDAB. The blends received or not 0.5 mol% DPI and 10% wt BAG or HAp. Icon was used as commercial control. The groups were characterized by XRD, FT-IR spectrometry, and SEM before and after simulated body fluid (SBF) immersion for up to 7 days. Polymerization kinetics (n =3 ), water sorption and solubility (n=10), and viscosity (n = 3) were surveyed. For polymerization kinetics, the samples were polymerized for 5 min and the data were obtained from 40 s and 5 min. Statistical analysis was made using ANOVA and Tukey's test (a = 0.05). After 7 days of SBF immersion, XRD and FT-IR showed that the HAp crystalline phase was present only in the HAp groups. A lower degree of conversion (DC) and polymerization rate were observed for the Icon and BAG groups, whereas HAp showed higher values. For the BAG group, DPI increased polymerization rate and DC in 40 s. After 5 min, all groups presented DC above 80%. In groups with particles, the HAp groups exhibited higher viscosity, whereas DPI groups showed a decrease in viscosity. Icon had the highest water sorption. To conclude, BAG neither improved the physicochemical properties studied, nor did it show bioactive properties. The addition of DPI reduced viscosity caused by particle addition and also attenuated the DC decrease caused by BAG addition. The addition of bioactive particles to infiltrants should be seen with caution because they increase viscosity and may not bring major clinical improvements that justify their use. DPI might be indicated only if any component is added to the infiltrant to act as a compensation mechanism

Trials

Soft palate defects created during oral cancer surgery may prevent complete palatal closure and trigger palatopharyngeal insufficiency. One current treatment employs a rigid obturator prosthesis; an extension of acrylic resin at the level of the hard palate ensures surface contact with the remaining musculature. Unfortunately, airflow escape often causes hypernasality, compromises speech intelligibility, and creates swallowing problems (including leakage of food and fluid into the nasal airway). We plan to test a new removable denture featuring a thick dental dam that serves as a membrane obturator. The principal objective of the clinical trial is a comparison of speech handicap levels after 1 month in patients with acquired velar insufficiencies who wear either the new device or a conventional, rigid obturator. The secondary objectives are between-device comparisons of the swallowing handicaps and the health-related qualities of life

RELATO DE DOIS CASOS DE MASTITE PÓS-PARTO EM CADELAS

Algumas das urgências reprodutivas presentes na espécie canina incluem distocias, piometra e mastite, sendo esta última, a inflamação bacteriana de uma ou mais glândulas mamárias, secundária ao parto em cadelas. Objetivou-se, com o presente relato, descrever dois casos de mastite em cadelas sem raça definida. Os dois casos foram diagnosticados por meio da anamnese e exame clínico, porém, no segundo caso foram realizados exames complementares (hemograma; cultura e antibiograma). O tratamento do primeiro caso foi feito com cefalexina e tintura de iodo topicamente nas tetas. Para o segundo caso, em decorrência da realização da cultura e antibiograma, detectou-se sensibilidade a alguns antibióticos e resistência a outros. Assim, o animal foi tratado com amoxicilina associada a ácido clavulânico. Em ambos os casos houve recuperação completa das pacientes. O diagnóstico precoce da enfermidade é importante devido ao caráter emergencial da doença. O tratamento, baseado em antimicrobianos, foi eficiente e adequado para os casos em questão

Genes flow by the channels of culture: the genetic imprint of matrilocality in Ngazidja, Comoros Islands

International audienc

Phytopathogenic nematofauna of commercial seeds of tropical forages

O objetivo deste trabalho foi identificar e quantificar a nematofauna fitopatogênica de sementes de forrageiras, destinadas aos mercados interno e externo. Examinaram-se sementes de Brachiaria brizantha (cvs. Marandu e Xaraés), B. decumbens cv. Basilisk, Panicum maximum (cvs. Massai, Mombaça e Tanzânia) e Stylosanthes capitata e S. macrocephala, componentes da cultivar Estilosantes Campo Grande. As extrações foram realizadas por flotação centrífuga, em solução de sacarose com caulim. Nas gramíneas, encontraram-se os gêneros Aphelenchoides e Ditylenchus. O maior número de espécimes de Aphelenchoides spp. foi observado nas sementes de 'Marandu', e, em seguida, nas sementes de 'Xaraés', 'Basilisk' e 'Tanzânia'. Quanto à densidade populacional de Ditylenchus spp., os maiores valores foram observados nas sementes de 'Marandu', 'Xaraés' e 'Basilisk'. Os resultados sugerem que pelo menos duas espécies de Aphelenchoides e Ditylenchus estão associadas às sementes de gramíneas forrageiras, destinadas ao mercado interno. Fitonematóides não são detectados em sementes de 'Estilosantes Campo Grande', tampouco nas cultivares Marandu, Mombaça e Tanzânia, destinadas à exportação.The objective of this work was to identify and quantify the phytopathogenic nematofauna of forage seeds destined for internal and external markets. Seeds of Brachiaria brizantha (cvs. Marandu and Xaraés), B. decumbens cv. Basilisk, Panicum maximum (cvs. Massai, Mombaça and Tanzania), and Stylosanthes capitata and S. macrocephala, components of cv. Estilosantes Campo Grande, were examined. The extractions were made by centrifugal flotation in solution of sucrose with kaolin. Aphelenchoides and Ditylenchus genera were detected in forage grasses. The highest number of Aphelenchoides spp. specimens was observed in seeds of cv. Marandu, followed by seeds of cvs. Xaraés, Basilisk, and Tanzania. Regarding Ditylenchus spp. population density, higher values were detected in seeds of cvs. Marandu, Xaraés, and Basilisk. The results suggest that two or more species of Aphelenchoides and Ditylenchus are associated to forage grass seeds destined for Brazilian market. Phytopathogenic nematodes are not detected in Estilosantes Campo Grande seeds, neither in seeds of cvs. Marandu, Mombaça and Tanzania destined for exportation

Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors

Made available in DSpace on 2018-12-11T17:23:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-01Context: Even though the majority of well-differentiated thyroid carcinoma (WDTC) is indolent, a number of cases display an aggressive behavior. Cumulative evidence suggests that the deregulation of DNA methylation has the potential to point out molecular markers associated with worse prognosis. Objective: To identify a prognostic epigenetic signature in thyroid cancer. Design: Genome-wide DNA methylation assays (450k platform, Illumina) were performed in a cohort of 50 nonneoplastic thyroid tissues (NTs), 17 benign thyroid lesions (BTLs), and 74 thyroid carcinomas (60 papillary, 8 follicular, 2 Hürthle cell, 1 poorly differentiated, and 3 anaplastic). A prognostic classifier for WDTC was developed via diagonal linear discriminant analysis. The results were compared with The Cancer Genome Atlas (TCGA) database. Results: A specific epigenetic profile was detected according to each histological subtype. BTLs and follicular carcinomas showed a greater number of methylated CpG in comparison with NTs, whereas hypomethylation was predominant in papillary and undifferentiated carcinomas. A prognostic classifier based on 21 DNA methylation probes was able to predict poor outcome in patients with WDTC (sensitivity 63%, specificity 92% for internal data; sensitivity 64%, specificity 88% for TCGA data). High-risk score based on the classifier was considered an independent factor of poor outcome (Cox regression, P < 0.001). Conclusions: The methylation profile of thyroid lesions exhibited a specific signature according to the histological subtype. A meaningful algorithm composed of 21 probes was capable of predicting the recurrence in WDTC.International Research Center, CIPE, A.C. Camargo Cancer Center and National Institute of Science and Technology in Oncogenomics, São Paulo 01509-010, SP, BrazilDepartment of Urology, Faculty of Medicine, UNESP, São Paulo State University, Botucatu 18618-970, SP, BrazilDepartment of Pathology, A.C. Camargo Cancer Center, São Paulo 01509-010, SP, BrazilEpigenetics Group; International Agency for Research on Cancer (IARC), Lyon 69372, FranceMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 1TH, United KingdomDepartment of Head and Neck Surgery and Otorhinolaryngology, A.C. Camargo Cancer Center, São Paulo 01509-010, SP, BrazilDepartment of Clinical Genetics, Vejle Hospital and Institute of Regional Health Research, University of Southern Denmark, Vejle, 7100, Denmar

Pyometra in a Bitch Possibly Caused by Simultaneous Administration of Levonorgestrel and Estradiol Cypionate

Background: Toxicological events in animals may be accidental or intentional and could occur in the home environment. These events could involve different agents such as pesticides, rodenticides, medicines, foods, and plants. Indiscriminate use of medication in pets by their owners is common. Self-medication of animals with drugs for human use can cause irreversible damage to their health. The emergency contraceptive pill (morning-after pill), comprising concentrated hormonal compounds, is sold freely in Brazil. The objective of this article was to report a case of pyometra in a bitch possibly caused by simultaneous administration of human emergency contraceptive pill along with a veterinary contraceptive medication.              Case: A 6-year-old bitch was referred to a Veterinary Medical Teaching Hospital for abdominal enlargement. According to the guardian, during estrus (30 days before the consultation) the female dog was covered. After intercourse, the owner administered a human emergency contraceptive pill (morning-after pill) and a veterinary contraceptive. Physical examination revealed severe dehydration (10%) and high temperature, besides the abdominal enlargement. The hemogram revealed leukocytosis with a left shift, characteristic of infection. After clinical examination, closed pyometra was suspected, and later confirmed by ultrasonography. Due to the poor clinical condition, fluid therapy was performed, and a systemic antibiotic was administered. After stabilization, the patient underwent ovariohysterectomy. In the postoperative period, the fluid therapy was continued, and antibiotic and anti-inflammatory drugs were administered. Two days after surgery, the patient was discharged for home recovery.  Discussion: Most cases of drug poisoning in animals involve female dogs, similar to the patient in this report. There is no theory elucidating the same, but the rate of incidence in female dogs has been reported to be higher than that in male dogs in the veterinary clinical routine. The administration of medicines at the guardian’s discretion, as seen in this case, is common in Brazil. The drugs involved may be of veterinary or human use. Drug intoxication is linked to the culture of self-medication. If the animal presents a symptom similar to that of a human, the guardian dispenses the same medicine used for him to their pet animal. Thus, it can be inferred that the guardian of the bitch in this report had the habit of self-medication and adopted the same conduct with the pet. The emergency contraceptive pill used here consisted of levonorgestrel, a progestin-type of hormone. No reports of levonorgestrel use have been reported in dogs; therefore, the mode of action of the drug in the canine species is unknown. The administration of progestogens in bitches is one of the main causes of reproductive diseases in the species. One of the diseases related to the use of contraceptives in bitches is pyometra. Despite the evidence, the human contraceptive cannot be determined as the cause of pyometra, because a veterinary contraceptive was also administered. Pyometra probably occurred due to the combined effect of both drugs. Thus, this case was diagnosed as drug intoxication. Veterinarians should be alert on this subject and invest in awareness and prevention of self-medication in animals by their guardians.